Located on the 2nd floor of Seneca City Hall, the Louise Matheson Bell Gallery has been featured on the South Carolina National Heritage Corridor Arts Trail.

The stained-glass windows depicting historic sites in Seneca are located in the arch at the front and rear of the Gallery. In 2006, stained glass artist Robert Crenshaw of Seneca created the design and crafted the windows. The project was funded by the Greys of Oconee chapter United Daughters of the Confederacy with proceeds from sales of Mrs. Bell's 1984 book, Rebels in Grey.

The gallery exhibitions rotate and features local artists exhibitions as well as historic exhibitions highlighting topics relevant to the local area.

Gallery hours coincide with operating hours of City Hall. The gallery is free to the public.